Handbook:AMD64/Blocks/ProfileChoice

No-multilib

In order to select a pure 64-bit environment, with no 32-bit applications or libraries, use a no-multilib profile:

root #eselect profile list

Available profile symlink targets:
  [1]   default/linux/amd64/13.0 *
  [2]   default/linux/amd64/13.0/desktop
  [3]   default/linux/amd64/13.0/desktop/gnome
  [4]   default/linux/amd64/13.0/desktop/kde
  [5]   default/linux/amd64/13.0/no-multilib

Next select the no-multilib profile:

root #eselect profile set 5

root #eselect profile list

Available profile symlink targets:
  [1]   default/linux/amd64/13.0
  [2]   default/linux/amd64/13.0/desktop
  [3]   default/linux/amd64/13.0/desktop/gnome
  [4]   default/linux/amd64/13.0/desktop/kde
  [5]   default/linux/amd64/13.0/no-multilib *

systemd

Those who desire systemd as their init system should select a profile with systemd somewhere in the profile name:

root #eselect profile set default/linux/amd64/13.0/systemd

root #eselect profile list

Available profile symlink targets:
  [10]  default/linux/amd64/13.0/developer
  [11]  default/linux/amd64/13.0/no-multilib
  [12]  default/linux/amd64/13.0/systemd *
  [13]  default/linux/amd64/13.0/x32
  [14]  hardened/linux/amd64

Tip
As seen above, full profile names can be used instead of the profile's associated numerical value.